Dipyridamole Dr. Reddy's 200 mg Modified-Release Capsules, Hard

• Keep this leaflet. You may need to read it again.
• If you have any further questions, ask your doctor or pharmacist.
• This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
• If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.

1. What Dipyridamole MR is and what it is used for
2. What you need to know before you take Dipyridamole MR
3. How to take Dipyridamole MR
4. Possible side effects
5. How to store Dipyridamole MR
6. Contents of the pack and other information

• are allergic to dipyridamole or any of the other ingredients of this medicine (listed in section 6).

Talk to your doctor or pharmacist before taking your medicine if:

• you are pregnant, likely to become pregnant, or if you are breast-feeding
• you have angina or other heart problems (including heart valve or circulation problems), or have had a recent heart attack
• you have myasthenia gravis (a condition characterised by extreme tiredness and muscle weakness)
• you have a bleeding disorder.

In people who have gallstones, the dipyridamole in this medicine can be absorbed into the gallstones.

If you are not sure if any of the above apply to you, talk to your doctor or pharmacist before taking Dipyridamole MR.

Dipyridamole can also be given by injection into a vein to test if the heart is functioning properly (myocardial imaging). This means that the test and your medicine may contain the same substance. If you are going to have this test, you should stop taking the capsules 24 hours before you have this test.

Please tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines, including medicines obtained without a prescription. This includes herbal medicines. This is because Dipyridamole MR can affect the way some other medicines work. Also some other medicines can affect the way Dipyridamole MR works.

In particular, tell your doctor or pharmacist if you are taking any of the following medicines:

• adenosine (for heart problems or tests on the heart)
• blood thinning medicines (such as warfarin). If so, tell them at your next visit to the anticoagulant clinic that you are now taking Dipyridamole MR.
• medicines for high or low blood pressure
• medicines for muscle weakness such as something called a ‘cholinesterase inhibitor’
• aspirin (or planning to take aspirin for any condition).

Do not take Dipyridamole MR at the same time as an alcoholic drink.

Tell your doctor if you are

• pregnant or likely to get pregnant
• breast-feeding

Your doctor will advise you whether to take Dipyridamole MR.

You may feel dizzy while taking Dipyridamole MR. If this happens do not drive or use any tools or machines.

Dipyridamole MR capsules contain the colouring agent ponceau 4R (E124), which may cause allergic reactions.

Do not take more than your doctor has prescribed.

It may cause symptoms such as feeling warm, sweating, racing of pulse, restlessness, weakness, dizziness and chest pain. If you take more than the recommended daily dose, consult a doctor or go to a hospital straight away. Take the medicine pack with you, even if there are no capsules left.

If you forget to take a dose, take it as soon as you remember but if it is nearly time for your next dose, skip the missed dose. Do not take a double dose to make up for a forgotten dose.

• breathing difficulties
• large welts or swelling of the skin near the eyes, lips, hands, feet or inside of the throat (which may cause difficulty breathing), runny nose and severe rash with itching.

Other side effects that have been reported are described below. They are listed as either very common, common or not known.

Very common (may affect more than 1 in 10 people)

• headache
• feeling dizzy
• feeling sick (nausea)
• diarrhoea

Common (may affect up to 1 in 10 people)

• muscle pain
• being sick (vomiting)
• worsening of symptoms of heart disease such as chest pain (angina) and heart beat problems (arrhythmias), fatigue, breathlessness

Not known (frequency cannot be estimated from the available data)

• hot flushes
• lowering of blood pressure or increased heart rate
• a blood problem called ‘thrombocytopenia’ which can cause bruising and prolonged bleeding from wounds including during or after surgery.

If you get any side effects, talk to your doctor, hospital pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme, Website: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store.

By reporting side effects you can help provide more information on the safety of this medicine.

The active substance (which makes the medicine work) is 200 mg dipyridamole.

The other ingredients are: hypromellose, tartaric acid, acacia, povidone, methacrylic acid-methyl methacrylate copolymer (1:2), hypromellose phthalate, dimethicone, triacetin, talc and stearic acid.

The HPMC capsule shell contains: Hypromellose, brilliant blue (E133), ponceau 4R (E124), quinoline yellow (E104), titanium dioxide (E171), Carrageenan and Potassium Acetate. The white imprinting ink contains: shellac, potassium hydroxide and titanium dioxide (E171).

Dipyridamole MR is a modified-release capsule filled with yellow to orange coloured pellets filled in size “0xel” hard capsules with opaque dark red cap and opaque dark orange body, imprinted ‘DPM’ on cap and ‘200’ on body with white ink.

Dipyridamole MR capsules are supplied in HDPE bottles, with desiccant.

Pack size: 60 capsules per bottle.