Lacidipine 6 mg Film-Coated Tablets

• Keep this leaflet. You may need to read it again.
• If you have any further questions, ask your doctor or pharmacist.
• This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
• If you get any side effects talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.

1. What Lacidipine is and what it is used for
2. What you need to know before you take Lacidipine
3. How to take Lacidipine
4. Possible side effects
5. How to store Lacidipine
6. Contents of the pack and other information

• if you are pregnant, likely to get pregnant or are breast-feeding
• if you are allergic to lacidipine, other calcium channel blocker medicines or any of the other ingredients of this medicine (listed in section 6)
• if you have the heart problem ‘aortic stenosis’. This is a narrowing of a valve in your heart, which restricts blood flow
• if you have had a heart attack within the last month.

Do not take Lacidipine if any of the above apply to you. If you are not sure, talk to your doctor or pharmacist before taking the medicine.

You should stop taking Lacidipine if you get chest pain (angina) or a fast, weak pulse, rapid shallow breathing, low blood pressure, cold clammy skin, blue lips or feel dizzy, faint, weak or sick.

Talk to your doctor or pharmacist before taking Lacidipine:

• if you have an uneven heart beat or any other heart problems
• if you have or have ever had any liver problems.

If you are having any blood tests, tell the person giving the test that you are taking this medicine. This is because Lacidipine can affect results relating to your liver.

Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.

This is because Lacidipine can affect the way some other medicines work. Also some other medicines can affect the way Lacidipine works.

In particular, tell your doctor or pharmacist if you are taking any of the following medicines:

• medicines for high blood pressure
• medicines to control your heart beat (called ‘anti-arrhythmics’)
• medicines for depression called ‘tricyclic antidepressants’
• sleeping tablets or sedatives
• antibiotics
• antihistamines - used for hayfever and other allergies
• cimetidine - used for stomach problems
• tetracosactide and corticosteroids.

Do not take this medicine with grapefruit juice.

Do not take Lacidipine if you are pregnant, likely to get pregnant or are breast-feeding.

You may feel dizzy while taking Lacidipine. If this happens, do not drive or use any tools or machines.

If you have been told by your doctor that you cannot tolerate or digest some sugars, talk to your doctor before taking this medicine.

If you take more of this medicine than you should, talk to a doctor or go to a hospital straight away. Take the medicine pack with you, even if there are no tablets left.

If you forget a dose in the morning, take it as soon as you remember it on the same day. However, if you remember the next day, take your normal dose on that morning. Do not take a double dose to make up for a forgotten dose.

• angina, this is a type of chest pain. This is uncommon in people taking Lacidipine and is more likely to occur when you start taking this medicine
• allergic reactions, the signs may include: rapid swelling of the face, mouth and throat which may cause difficulty breathing.

The side effects described below have been experienced by people taking Lacidipine. They are listed as either common, uncommon, rare or very rare.

Common (may affect up to 1 in 10 people)

• dizziness, headache, fast or uneven heart beat (also called palpitations), flushing, swelling particularly of the ankles. These side effects usually go away as treatment continues
• fast heart beat
• upset stomach, feeling sick (nausea)
• rash, redness of the skin, itching
• an increase in the amount of water (urine) that you pass
• feeling weak
• changes in results of blood tests relating to your liver

Uncommon (may affect up to 1 in 100 people)

• chest pain (angina) including chest pain that is getting worse
• low blood pressure for example feeling faint, fainting
• swelling of the gums

Rare (may affect up to 1 in 1,000 people)

• rapid swelling of the face, mouth and throat which may cause difficulty breathing
• nettle rash (urticaria)
• muscle cramps

Very rare (may affect up to 1 in 10,000 people)

• tremor
• depression

If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme, website www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. By reporting side effects you can help provide more information on the safety of this medicine.

The active substance is lacidipine. Each tablet contains 2 mg, 4 mg or 6 mg.

The other ingredients are lactose monohydrate, povidone, crospovidone and magnesium stearate. The film coating contains hypromellose, titanium dioxide and macrogol 400.

The 2 mg tablets are film-coated, round and white in colour. They have the logo on one side and the code ‘225’ on the other.

The 4 mg tablets are film-coated, oval and white in colour. They have the logo on one side and the codes ‘2’ and ‘24’ separated by a break line on the other.

The 6 mg tablets are film-coated, oval and white in colour. They have the logo on one side and the code ‘226’ on the other.

Lacidipine tablets are available in blister packs of 28 tablets.

Not all pack sizes may be marketed.