Liothyronine sodium 20 micrograms Hard Capsules

• Keep this leaflet. You may need to read it again.
• If you have any further questions, ask your doctor or pharmacist.
• This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs or illness are the same as yours.
• If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.

The name of your product is Liothyronine sodium 5 micrograms, 10 micrograms or 20 micrograms Hard Capsules, but it will be referred to as Liothyronine sodium Capsules throughout this leaflet.

1. What Liothyronine sodium Capsules are and what they are used for
2. What you need to know before you use Liothyronine sodium Capsules
3. How to use Liothyronine sodium Capsules
4. Possible side effects
5. How to store Liothyronine sodium Capsules
6. Contents of the pack and other information

• know that you are allergic to liothyronine sodium or any of the other ingredients (listed in section 6 at the end of this leaflet)
• have angina (chest pain when exercising) or conditions affecting your heart or circulation
• are suffering from thyrotoxicosis (condition due to over activity of the thyroid gland).

Speak to your doctor before you take this medicine if any of the above applies to you.

Talk to your doctor or pharmacist before taking Liothyronine sodium Capsules if you:

• are suffering from diabetes Liothyronine sodium Capsules may raise blood sugar levels
• are suffering from a condition called myxoedema (which can happen when you have a problem with your thyroid gland) which makes your skin look swollen and dry
• are elderly (65 years or over)
• have suffered from low levels of thyroid hormone in your body for a long time, as this may affect how your adrenal glands work. You may be given additional medication (corticosteroids) if this is the case
• are suffering from any heart problems
• have increased blood pressure
• suffer from increased heart rate, sleeplessness, loose watery stools (suggesting increased metabolism) on initiation of treatment, a dose reduction would be required
• are starting treatment, as an ECG test (a recording of the electrical activity of your heart) will be valuable
• are pregnant or breast feeding.

Speak to your doctor before you take this medicine if any of the above applies to you.

Tell your doctor or pharmacist if you are taking or have recently taken or might take any other medicines.

Liothyronine sodium Capsules may affect or be affected by the following medicines:

• Anticoagulants (e.g. warfarin) used to thin the blood and prevent blood clots
• Anticonvulsants (e.g. carbamazepine or phenytoin) used to prevent fits
• Insulin and other treatments for diabetes
• Medicines called cardiac glycosides (e.g. digoxin) used to treat heart conditions such as heart failure
• Tricyclic antidepressants (e.g. amitriptyline / imipramine) used to treat depression
• Colestyramine / colestipol which reduces the level of cholesterol (fats) in the blood
• Oral contraceptives (‘the pill')
• Amiodarone, used to treat irregular heart beats
• Barbiturates, used to induce sleep and decrease anxiety
• Primidone, used for seizures or fits.

If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine. The decision on whether it is best to take Liothyronine sodium Capsules during pregnancy or breast feeding will be made by your doctor. Ask your doctor or pharmacist for advice before taking any medicines.

This medicine contains less than 1 mmol sodium (23 mg) per each 5 micrograms, 10 micrograms or 20 micrograms hard capsule, that is to say essentially ‘sodium-free'.

The dose will depend upon your condition, ranging from 10 micrograms to 60 micrograms daily in divided doses.

The dose may be started at 5 micrograms a day.

• Please note that your doctor will monitor your thyroid function regularly to make sure that you are given the right dose for your condition.

This may cause agitation, confusion, headache, sweating and a rapid pulse. If you take too many tablets contact your doctor or nearest hospital casualty department as soon as possible.

Take any remaining tablets and this leaflet with you so the medical staff will know what you have taken.

Take the next dose at the correct time and then go on as before. It is important, in order for your medicine to work, that doses are not forgotten.

Do not take a double dose to make up for a forgotten dose.

Do not stop taking Liothyronine sodium Capsules unless your doctor tells you to.

If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via Yellow Card Scheme, Website: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. By reporting side effects you can help provide more information on the safety of this medicine.

Liothyronine sodium 5 micrograms Capsules

• Each capsule contains 5 micrograms of the active substance liothyronine sodium.
• The other ingredients are: maize starch, magnesium stearate (E572).
• Liothyronine sodium 5 micrograms capsule shell contains gelatin.

Liothyronine sodium 10 micrograms Capsules

• Each capsule contains 10 micrograms of the active substance liothyronine sodium.
• The other ingredients are: maize starch, magnesium stearate (E572).
• Liothyronine sodium 10 micrograms capsule shell contains: gelatin and titanium dioxide (E171).

Liothyronine sodium 20 micrograms Capsules

• Each capsule contains 20 micrograms of the active substance liothyronine sodium.
• The other ingredients are maize starch, magnesium stearate (E572).
• Liothyronine sodium 20 micrograms capsule shell contains: gelatin, titanium dioxide (E171) and yellow iron oxide (E172).

Liothyronine sodium 5 micrograms Capsules are size 4, natural transparent, hard gelatin capsules.

Liothyronine sodium 10 micrograms Capsules are size 4, opaque white, hard gelatin capsules.

Liothyronine sodium 20 micrograms Capsules are size 4, opaque ivory, hard gelatin capsules.

They are packed in opaque PVC/PVDC/ aluminium blisters. Each blister contains 7 or 10 capsules.

Pack sizes: 28, 56, 100, 112 hard capsules.

Not all pack sizes may be marketed.