Lacidipine 4mg film-coated tablets

• Keep this leaflet. You may need to read it again.
• If you have any further questions, ask your doctor or pharmacist.
• This medicine has been prescribed for you only.
  Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
• If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.

1. What Lacidipine tablets are and what they are used for
2. What you need to know before you use Lacidipine tablets
3. How to use Lacidipine tablets
4. Possible side effects
5. How to store Lacidipine tablets
6. Contents of the pack and other information

• If you are pregnant, likely to get pregnant or are breast-feeding
• If you are allergic to lacidipine, other calcium channel blocker medicines or any of the other ingredients of this medicine (listed in section 6)
• If you have the heart problem ‘aortic stenosis’.This is a narrowing of a valve in your heart, which restricts blood flow
• If you have had a heart attack within the last month

Do not take Lacidipine tablets if any of the above apply to you. If you are not sure, talk to your doctor or pharmacist before taking Lacidipine tablets.

You should stop taking lacidipine if you get chest pain (angina) or a fast, weak pulse, rapid shallow breathing, low blood pressure, cold clammy skin, blue lips or feel dizzy, faint, weak or sick.

Talk to your doctor or pharmacist before using Lacidipine tablets:

• if you have an uneven heart beat or any other heart problems,
• if you have or have ever had any liver problems.

Lacidipine tablets should not be administered to children and adolescents under 18 years.

Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines. This includes herbal medicines. This is because Lacidipine tabletst can affect the way some other medicines work. Also some other medicines can affect the way Lacidipine tablets works.

In particular, tell your doctor or pharmacist if you are taking any of the following medicines:

• medicines for high blood pressure
• medicines to control your heart beat (called ‘anti-arrhythmics’)
• medicines for depression called ‘tricyclic antidepressants’
• sleeping tablets or sedatives
• antibiotics (e.g. rifampicin)
• antihistamines – used for hay fever and other allergies
• cimetidine – used for stomach problems,
• tetracosactide and corticosteroids

If you are having any blood tests, tell the person giving the test that you are taking this medicine. This is because Lacidipine tablets can affect results relating to your liver.

Lacidipine tablets can be taken with or without a meal. Do not take this medicine with grapefruit juice.

If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine. There is no information on the safe use of Lacidipine tablets in pregnancy.

Do not take Lacidipine tablets if you are pregnant, likely to get pregnant or are breast-feeding.

The active substance and excipients of Lacidipine tablets can pass into breast milk. If you are breast-feeding, check with your doctor before starting treatment with Lacidipine tablets.

This medicine may cause dizziness. If you experience this side effect, do not drive vehicles or operate machines which require your attention.

If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicinal product.

If you take more of this medicine than you should, talk to a doctor or go to a hospital straight away. Take the medicine pack and the leaflet with you, even if there are no tablets left.

Medical treatment can be necessary. Effects of overdose will likely cause irregular heartbeat, rapid shallow breathing, low blood pressure, cold humid skin or feeling dizzy, fainting, weakness or nausea.

If you forget a dose in the morning, take it as soon as you remember it on the same day. However, if you remember the next day, take your normal dose on that morning.

Do not take a double dose to make up for a forgotten dose.

Take Lacidipine tablets for the period of time prescribed by your doctor. Do not stop taking Lacidipine tablets unless instructed by your doctor.

• angina, this is a type of chest pain. This is uncommon in people taking Lacidipine and is likely to occur when you start taking this medicine.
• allergic reactions, the signs may include: rapid swelling of the face, mouth and throat which may cause difficulty breathing.

The side effects have been divided according to their frequency:

Common (may affect up to 1 in10 people):

• Dizziness, headache, fast or uneven heart beat (also called palpitations), flushing, swelling particularly of the ankles. These side effects usually go away as treatment continues
• fast heart beat,
• upset stomach or feeling sick (nausea),
• rash, redness of the skin, itching,
• an increase in the amount of water (urine ) that you pass,
• feeling weak (asthenia),
• changes in results of blood tests relating to your liver.

Uncommon (may affect up to 1 in 100 people):

• chest pain (angina) including chest pain that is getting worse,
• low blood pressure for example feeling faint, fainting,
• swelling of the gums.

Rare (may affect up to 1 in 1,000 people):

• rapid swelling of the face, mouth and throat which may cause difficulty breathing,
• nettle rash (urticaria),
• muscle cramps.

Very rare (may affect up to 1 in 10,000 people):

• shaking (tremor),
• depression.

If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. By reporting side effects you can help provide more information on the safety of this medicine.

The active substance is lacidipine.

Lacidipine 2 mg film-coated tablets: each tablet contains lacidipine 2 mg.

Lacidipine 4 mg film-coated tablets: each tablet contains lacidipine 4 mg.

The other ingredients are:

core: lactose, povidone, magnesium stearate;

film-coat: hypromellose, talc, propylene glycol, titanium dioxide (E171).

Lacidipine 2 mg film-coated tablets:

white, round [diameter 8.1 mm], biconvex, film-coated tablets

Lacidipine 4 mg film-coated tablets:

white, oval [13 mm ×7.4 mm], biconvex, film-coated tablets with score line on one side.

The tablet can be divided into equal doses. If, in accordance with the recommended dosage, you take a half tablet of 4 mg, then the unused half should be kept out of direct light and taken within 48 hours.

Lacidipine tablets are packed into OPA/Aluminium/PVC/Aluminium blisters, placed along with the leaflet into a carton.

Pack sizes:

Lacidipine 2 mg film-coated tablets – 7, 14, 28, 56 film-coated tablets

Lacidipine 4 mg film-coated tablets – 7, 14, 28, 56 film-coated tablets

Not all pack sizes may be marketed.

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