Patient Leaflet Updated 03-Oct-2024 | Zentiva
Desmopressin 120 micrograms & 240 micrograms sublingual tablets
Desmopressin 120 micrograms sublingual tablets
Desmopressin 240 micrograms sublingual tablets
desmopressin (as acetate)
This is a serious problem and may lead to convulsions.
Now read the rest of this leaflet. It includes other important information on the safe and effective use of this medicine.
1.What Desmopressin is and what it is used for
2.What you need to know before you take Desmopressin
3.How to take Desmopressin
4.Possible side effects
5.How to store Desmopressin
6.Contents of the pack and other information
The name of your medicine is Desmopressin 120 and 240 microrgams sublingual tablets (called Desmopressin throughout this leaflet). They are oral lyophilisates, they look like tablets but are much softer and lighter. Intended for sublingual use (to be placed under the tongue where it will dissolve completely).
Desmopressin is available in two strengths: 120 and 240 micrograms. It contains Desmopressin acetate, an antidiuretic (reduces urine production)..
Desmopressin is used to treat:
You should avoid drinking large amounts of fluid while you are being treated with Desmopressin, as this could lead to a build up of water which dilutes the salt in the body. This is a serious problem and may lead to convulsions.
Please consult your doctor before taking Desmopressin if you:
Please inform your doctor or pharmacist if you:
If you are pregnant or planning a pregnancy, please inform your doctor before you take Desmopressin, as blood pressure monitoring is recommended due to the increased risk of pre-eclampsia (a condition in pregnant women that can cause serious complications). Symptoms of pre-eclampsia include high blood pressure, oedema (swelling due to the build up of fluid) and proteinuria (protein in the urine).
If you are breast-feeding ask your doctor or pharmacist for advice before taking Desmopressin.
Desmopressin contains lactose (a type of sugar). If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.
Desmopressin contains sodium. This medicine contains less than 1 mmol sodium (23 mg) per sublingual tablet, that is to say essentially ‘sodium-free’.
It is important to use this medicine as directed by your doctor. Desmopressin is intented for sublingual use (to be placed under the tongue where it will dissolve completely).
Do NOT take more than the prescribed dose in any 24 hour period.
If you have the impression that the effect of Desmopressin is too strong or too weak, talk to your doctor or pharmacist.
Treatment of diabetes insipidus:
Your doctor will prescribe the dose most suitable for you. The most common doses in adults and children are either one Desmopressin 60 micrograms or one Desmopressin 120 micrograms three times a day.
Treatment of extreme thirst and the continuous production of large volumes of dilute urine following surgical removal of the pituitary gland:
Your doctor will prescribe the most suitable dose for you based on the concentration of your urine.
If you take more Desmopressin than you should or if, talk to your doctor or pharmacist immediately.
Do not take a double dose to make up for a forgotten tablet.
If you are a patient with diabetes insipidus, please consult your doctor or pharmacist immediately.
Like all medicines, this medicine can cause side effects although not everybody gets them.
You should avoid drinking large amounts of fluid while you are being treated with Desmopressin, as this could lead to a build up of water which dilutes the salt in the body. This is a serious problem and may lead to convulsions.
If you experience any of the above side effects, you should contact your doctor or go to the nearest casualty department immediately.
Most people using Desmopressin find it causes them no problems. However, common side effects can include:
Very rare cases of emotional disorders including aggression in children have also been reported.
If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store.
By reporting side effects, you can help provide more information on the safety of this medicine.
Keep this medicine out of the sight and reach of children.
Do not use this medicine after the expiry date which is stated on the blister, label, carton or bottle after EXP. The expiry date refers to the last day of that month.
Store in the original blister in order to protect from moisture. This medicine does not require any special temperature storage conditions.
Store in the original package. Keep the bottle tightly closed in order to protect from moisture. Do not store above 30 °C.
Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.
Desmopressin 120 micrograms sublingual tablets
White or almost white, octagonal, biconvex tablet debossed with ‘II’ on one side and plain on other side, with 6.5 mm diameter and 2 mm thickness.
Desmopressin 240 micrograms sublingual tablets
White or almost white, square, biconvex tablet debossed with ‘III’ on one side and plain on other side, with 6 mm length/ width and 2 mm thickness.
Desmopressin is supplied in a carton box containing OPA/Al/PVC/PE-Al blisters with integrated desiccant layer with 10 tablets each, in pack sizes of 10, 30, 60, 90 and 100 sublingual tablets or in HDPE bottles with PP caps with integrated desiccant containing 30 or 100 sublingual tablets.
Not all pack sizes may be marketed.
Marketing Authorisation Holder:
Manufacturer(s)
or
This leaflet was last revised in July 2024
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