Incipient cardiac failure should be controlled before treatment with indoramin.
Caution should be observed in prescribing indoramin for patients with hepatic or renal insufficiency.
A few cases of extrapyramidal disorders have been reported in patients treated with indoramin. Caution should be observed in prescribing indoramin in patients with Parkinson's disease.
In animals and in the one reported case of overdose in humans, convulsions have occurred. Due consideration should be given, and great caution exercised in the use of indoramin in patients with epilepsy.
The 'Intraoperative Floppy Iris Syndrome (IFIS, a variant of small pupil syndrome) has been observed during cataract surgery in some patients on or previously treated with tamsulosin. Isolated reports have also been received with other alpha-1 blockers and the possibility of a class effect cannot be excluded. As IFIS may lead to increased procedural complications during the cataract operation current or part use of alpha-1 blockers should be made known to the ophthalmic surgeon in advance of surgery.
Caution should be observed in prescribing indoramin for patients with a history of depression.
Clearance of indoramin may be affected in the elderly. A reduced dose, and/or reduced frequency of dosing may be sufficient in some elderly patients.
Patients with rare hereditary problems of galactose intolerance, total lactase deficiency or glucose-galactose malabsorption should not take this medicine.