Jinarc is a specialist product for which additional training is available prior to prescribing. If you wish to register as a prescriber to receive notification of materials update and yearly training reminders, please visit https://www.jinarctraining.co.uk/. This guide has been developed for prescribers and healthcare professionals (HCPs) involved in the treatment of patients using Jinarc (tolvaptan). This document summarises important information on the potential risk of hepatic toxicity and provides guidance on how to manage this risk. In addition, it provides important information about pregnancy prevention before and during the treatment with Jinarc.