Important information about ▼KIMMTRAK® (tebentafusp) Information to assist healthcare professionals: • Description of Cytokine Release Syndrome (CRS) and Acute Skin Reactions in patients treated with tebentafusp, including severity, frequency, time to onset, treatment, and resolution. • How to manage CRS and acute skin reactions based on severity grade including information when corticosteroid premedication is recommended. • Monitoring requirements for patients during the first three infusions and for subsequent infusions. • How to minimise the risk of hypotension associated with CRS. • Description of the ECG schedule and management requirements based on the ECG results. • Recommendation to carefully monitor patients with cardiac disease, QT prolongation and risk factors for cardiac failure. • Information on the importance of informing patients of the risk of CRS and Acute Skin Reactions, and the need to immediately contact their doctor or nurse if they develop any symptoms of CRS or Acute Skin