This medicine is available without prescription. However, you still need to take Cystopurin carefully to get the best results from it.

• Keep this leaflet. You may need to read it again.
• Ask your pharmacist if you need more information or advice.
• You must contact a doctor if your symptoms worsen or do not improve.
• If you have any unusual effects after using this product, tell your doctor or pharmacist.

1. What is Cystopurin and what is it used for?
2. Before you take Cystopurin
3. How to take Cystopurin
4. Possible side effects
5. How to store Cystopurin
6. Further information

• If you are allergic (hypersensitive) to potassium citrate or any of the other ingredients of Cystopurin (see Section 6 ‘Further Information’).

• You are a man.
• You are under 18 years of age.
• You have a history of heart problems or kidney disease.
• Your urine is dark or cloudy, or has blood in it.
• You have unusually heavy vaginal discharge.
• You have stomach, groin or back pain.
• You have high body temperature and general tiredness.
• You suffer from phenylketonuria, since this product contains aspartame.

This medicine contains 40 mg aspartame in each sachet. Aspartame is a source of phenylalanine. It may be harmful if you have phenylketonuria (PKU), a rare genetic disorder in which phenylalanine builds up because the body cannot remove it properly.

This medicine contains less than 1 mmol sodium (23 mg) per sachet, that is to say essentially ‘sodium-free’.

Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.

In particular, tell your doctor or pharmacist if you are taking:

• Diuretics that retain potassium, such as amiloride.
• Aldosterone antagonists, such as spironolactone.
• ACE inhibitors or aliskiren (for high blood pressure).
• Angiotensin-II receptor antagonists, such as losartan (for high blood pressure or heart failure).
• Methenamine (an antibacterial).
• Ciclosporin or tacrolimus (immunosuppressants used to reduce risk of organ transplant rejection).

Cystopurin granules should be diluted in water. They can be taken with or without food.

While suffering from cystitis avoid alcohol, fruit juices, coffee and strong tea. You should also try to drink as much water as possible (at least 8 glasses per day).

As with all medicines, Cystopurin should not be taken during pregnancy or breast-feeding, unless you are advised to do so by your doctor.

• Take the contents of one sachet dissolved in a small glass of cold water (200ml), three times daily for two days.
• All six sachets must be taken to complete the course of treatment.

• Use only after advice from your doctor, and follow his/her directions carefully.

Cystopurin is not recommended for children under 6 years.

You should consult your doctor if symptoms return or persist after 48 hours of treatment.

Tell your doctor straight away or contact the Accident and Emergency Department of your nearest hospital.

Prolonged high doses can cause high blood levels of potassium (hyperkalaemia), which can cause abnormal heart rhythm.

If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store.

By reporting side effects you can help provide more information on the safety of this medicine.

• The active substance is potassium citrate (3g).
• The other ingredients are mannitol (E421), citric acid (E330), aspartame (E951), cranberry flavour (flavour contains natural cranberry extracts with maltodextrin, silicon dioxide (E551), carmine (E120) and triacetin (E1518)).
  See Section 2 ‘Important information about some of the ingredients of Cystopurin’ for aspartame advice.

Cystopurin is available in packs of 6 sachets containing 3g of pink-brown granules.

Remember: If you have any doubts about using Cystopurin^® correctly, seek the advice of your doctor or pharmacist.

Cystitis is a distressing condition caused by an infection and/or inflammation of the bladder. It is normally no more than a painful nuisance and only rarely becomes more serious. Cystitis will occur in 4 out of 5 women at least once in their lifetime, so it is a very common complaint and the attacks usually cause no lasting damage.

Cystitis can also occur in men and children, but this is quite rare and medical advice should be sought.

There are two types of cystitis: bacterial cystitis and non-bacterial cystitis.

• Bacterial cystitis is caused by bacteria that reach the bladder from the bowel. This may occur during sexual intercourse, or be due to ineffective/infrequent hygiene.
• Non-bacterial cystitis can be caused by a number of triggers including certain soaps, deodorants, insufficient water-based liquid intake, or even tight trousers.

The most common symptoms of cystitis are:

• A sharp stinging sensation on passing water.
• An urge to pass water more frequently.

• Try to drink plenty of fluids every day.
• Take care of your personal hygiene. It can help if you and your partner wash carefully before and after sexual intercourse.
• Always go to the toilet as soon as you feel the need to pass water. Keeping your bladder flushed will help it work normally.

• Try to avoid washing with perfumed soaps or using deodorants or perfumes around the vaginal area.

Further information on cystitis can be obtained from your doctor or pharmacist or by contacting: