The data given for frequency of adverse reactions is based on the following categories:
Very common (≥ 1/10)
Common (≥ 1/100 to < 1/10)
Uncommon (≥ 1/1,000 to < 1/100)
Rare (≥ 1/10,000 to 1/1,000)
Very rare (< 1/10,000)
Not known (frequency cannot be estimated from the available data)
Metabolism and nutrition disorders
Frequency unknown: Hypercalcaemia
Immune system disorders
Frequency unknown: Hypersensitivity reactions (including swelling, oedema and face oedema)
Skin and subcutaneous tissue disorders:
Rare: Skin irritation (e.g. burning, erythema), itching, contact dermatitis, worsening of psoriasis.
Skin irritation and itching are generally mild and transient
Frequency unknown: rash (erythematous, macular, papular, vesicular).
Reporting of suspected adverse reactions
Reporting suspected adverse reactions after authorisation of the medicinal product is important. It allows continued monitoring of the benefit/risk balance of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme, Website: www.mhra.gov.uk/yellowcard or search for MHRA Yellow card in the Google Play or Apple App Store.