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Panadol Advance 500 mg Tablets (GSL)

Active Ingredient:
paracetamol
About Medicine
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Healthcare Professionals (SmPC) Patient Leaflet (PIL)
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The Patient Information Leaflet (PIL) is the leaflet included in the pack with a medicine.
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Last updated on emc: 26 Feb 2025
{pdf} View or print the patient leaflet as PDF

Below is a text only representation of the Patient Information Leaflet (ePIL).

The text only version may be available in large print, Braille or audio CD. For further information call emc accessibility on {phone} 0800 198 5000. The product code(s) for this leaflet is: PL 44673/0080.

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Panadol Advance 500 mg Tablets

PATIENT INFORMATION LEAFLET

Panadol Advance 500 mg Tablets

Paracetamol

Please read right through this leaflet before you start using this medicine.

This medicine is available without prescription, but you still need to use Panadol Advance 500 mg Tablets carefully to get the best results from them.

  • Keep this leaflet, you may need to read it again.
  • If you have any questions, or if there is anything you do not understand, ask your pharmacist.
  • Contains paracetamol.

In this leaflet:

1. What Panadol Advance 500 mg Tablets do
2. Check before you take Panadol Advance 500 mg Tablets
3. How to take Panadol Advance 500 mg Tablets
4. Possible side effects
5. How to store Panadol Advance 500 mg Tablets
6. Further information

1. What Panadol Advance 500 mg Tablets do

Panadol Advance 500 mg Tablets are faster absorbed than standard paracetamol tablets. They are suitable for the relief of headache, tension headache, migraine, backache, rheumatic and muscle pain, toothache and period pain.

They also relieve sore throat and the fever, aches and pains of colds and flu and are recommended for the relief of pain due to mild arthritis.

The active ingredient is paracetamol which is a painkiller and also reduces your temperature when you have a fever.

2. Check before you take Panadol Advance 500 mg Tablets
Do not take Panadol Advance 500 mg Tablets:
  • if you have ever had an allergic reaction to paracetamol or to any of the other ingredients (listed in Section 6)
  • if you are taking any other prescription or non-prescription medicines containing paracetamol to treat pain, fever, symptoms of cold and flu, or to aid sleep.

Ask your doctor before you take this medicine:
  • if you suffer from mild arthritis and need to take painkillers every day.
  • if you have liver or kidney problems
  • if you are underweight
  • if you regularly drink alcohol
  • If you have severe infection or illnesses, including severe renal impairment or sepsis (when bacteria and their toxins circulate in the blood leading to organ damage), or you suffer from malnutrition, chronic alcoholism or if you are also taking flucloxacillin (an antibiotic). A serious condition called metabolic acidosis (a blood and fluid abnormality) has been reported in patients in these situations when paracetamol is used at regular doses for a prolonged period or when paracetamol is taken together with flucloxacillin.

Symptoms of metabolic acidosis may include:

  • serious breathing difficulties with deep rapid breathing
  • drowsiness
  • feeling sick (nausea) and being sick (vomiting)
  • loss of appetite

During treatment with Panadol Advance 500 mg Tablets, tell your doctor straight away if you get a combination of these symptoms.

You may need to avoid using this product altogether or limit the amount of paracetamol that you take.

If you are taking other medicines

Talk to your doctor or pharmacist before taking these tablets if you are taking any prescribed medicines; particularly metoclopramide or domperidone (for nausea [feeling sick] or vomiting [being sick]) or colestyramine (to lower blood cholesterol). If you take blood thinning drugs (anticoagulants e.g. warfarin) and you need to take a pain reliever on a daily basis, talk to your doctor because of the risk of bleeding. But you can still take occasional doses of Panadol Advance 500 mg Tablets at the same time as anticoagulants. Please inform your doctor or pharmacist if you are taking flucloxacillin (antibiotic), due to a serious risk of blood and fluid abnormality (called metabolic acidosis) that must have urgent treatment (see section 2).

Pregnancy and breast feeding

Talk to your healthcare professional before taking Panadol Advance 500 mg Tablets if you are pregnant. You can take this product whilst breast feeding.

3. How to take Panadol Advance 500 mg Tablets

Adults (including the elderly) and children aged 16 years and over:

Swallow 1-2 tablets every 4 to 6 hours as needed.

Do not take more than 8 tablets in 24 hours.

Children aged 10-15 years:

Give 1 tablet every 4 to 6 hours as needed. Do not give more than 4 tablets in 24 hours.

Do not give for more than 3 days at a time unless your doctor tells you to.

  • Do not take more frequently than every 4 hours.
  • Do not take more than the recommended dose.
  • Do not give to children under 10 years.

If you take too many tablets

Talk to a doctor at once if you take too much of this medicine even if you feel well. This is because too much paracetamol can cause delayed, serious liver damage.

If your symptoms continue or your headache becomes persistent, see your doctor.

4. Possible side effects

Like all medicines, Panadol Advance 500 mg Tablets can have side effects but not everybody gets them. A small number of people have had side effects.

Very rare cases of serious skin reactions have been reported.

Stop taking the medicine and tell your doctor immediately if you experience:

  • Allergic reactions which may be severe such as skin rash and itching sometimes with swelling of the mouth or face or shortness of breath
  • Skin rash or peeling, or mouth ulcers
  • Breathing problems. These are more likely if you have experienced them before when taking other painkillers such as ibuprofen and aspirin
  • Unexplained bruising or bleeding
  • Nausea, sudden weight loss, loss of appetite and yellowing of the eyes and skin.
  • A serious condition that can make blood more acidic (called metabolic acidosis), in patients with severe illness using paracetamol (frequency not known - see section 2).

Reporting of side effects

If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet.

You can also report side effects directly via the Yellow Card Scheme at www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. By reporting side effects, you can help provide more information on the safety of this medicine.

5. How to store Panadol Advance 500 mg Tablets

Keep out of the sight and reach of children.

Do not use this medicine after the ‘EXP’ date shown on the pack.

Store below 30°C.

6. Further information

Active ingredient: Each tablet contains Paracetamol 500 mg.

Other ingredients: Pregelatinised starch, calcium carbonate, alginic acid, crospovidone, povidone, magnesium stearate and colloidal anhydrous silica.

The tablet coating contains opadry white and carnauba wax.

Packs of Panadol Advance 500 mg Tablets contain 16 or 30 tablets.

The marketing authorisation holder is

Haleon UK Trading Limited
The Heights
Weybridge
KT13 0NY
U.K.

and all enquiries should be sent to this address.

The manufacturer is

Haleon Ireland Dungarvan Limited
Knockbrack
Dungarvan
Co. Waterford
X35 RY76
Ireland

This leaflet was last revised in January 2025.

Trade Marks are owned by or licensed to the Haleon group of companies.

NPA017140

Haleon UK Trading Limited
Company image
Address
The Heights, Weybridge, Surrey, KT13 0NY, UK
Medical Information e-mail
[email protected]
Customer Care direct line
0800 783 8881
Medical Information Direct Line
0800 783 8881
WWW
https://www.haleon.com/