• Keep this leaflet. You may need to read it again.
• If you have any further questions, ask your doctor or pharmacist.
• This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
• If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. See section 4.

1. What Dorzolamide is and what it is used for
2. What you need to know before you use Dorzolamide
3. How to use Dorzolamide
4. Possible side effects
5. How to store Dorzolamide
6. Contents of the pack and other information

• if you are allergic to dorzolamide hydrochloride or any of the other ingredients of this medicine (listed in section 6)
• if you have severe kidney impairment or problems or a prior history of kidney stones.

Talk to your doctor or pharmacist before using Dorzolamide

Tell your doctor or pharmacist about any medical problems you have now or have had in the past, including eye problems and eye surgeries, and about any allergies to any medications.

If you develop any eye irritation or any new eye problems such as redness of the eye or swelling of the eyelids, contact your doctor immediately.

If you suspect that dorzolamide is causing an allergic reaction (for example, skin rash, severe skin reaction or itching), stop using this medicine and contact your doctor immediately.

Dorzolamide has been studied in infants and children less than 6 years of age who have raised pressure in the eye(s) or have been diagnosed with glaucoma. For more information, talk to your doctor.

In studies with Dorzolamide, the effects of this medicine were similar in both elderly and younger patients.

Tell your doctor about any liver problems you now have or have suffered from in the past.

Tell your doctor or pharmacist if you are using, have recently used or might use any other medicines (including eye drops).

This is particularly important if you are taking another carbonic anhydrase inhibitor such as acetazolamide, or a sulpha drug.

If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.

Pregnancy

You should not use this medicine during pregnancy. Tell your doctor if you are pregnant or intend to become pregnant.

Breast-feeding

If treatment with this medicine is required, breast-feeding is not recommended. Tell your doctor if you are breast-feeding or intend to breast-feed.

No studies on the effects on the ability to drive or use machines have been performed. There are side effects associated with dorzolamide, such as dizziness and blurred vision, which may affect your ability to drive and/or operate machinery. Do not drive or operate machinery until you feel well or your vision is clear.

This medicine contains the preservative benzalkonium chloride.

Benzalkonium chloride may be absorbed by soft contact lenses and may change the colour of the contact lenses. You should remove contact lenses before using this medicine and put them back 15 minutes afterwards.

Benzalkonium chloride may also cause eye irritation, especially if you have dry eyes or disorders of the cornea (the clear layer at the front of the eye). If you feel abnormal eye sensation, stinging or pain in the eye after using this medicine, talk to your doctor.

It is recommended that you wash your hands before putting in your eye drops.

It may be easier to apply your eye drops in front of a mirror.

1. Before using the medication for the first time, be sure that the tamper-proof seal on the bottle neck is unbroken. A gap between the bottle and the cap is normal for an unopened bottle.
2. Take off the cap of the bottle.
3. Tilt your head back and gently pull your lower eyelid down to form a small pocket between your eyelid and your eye.
4. Invert the bottle and squeeze it until a single drop is dispensed into the eye as directed by your doctor. DO NOT TOUCH YOUR EYE OR EYELID WITH THE DROPPER TIP.
5. Repeat steps 2 & 3 with the other eye if instructed to do so by your doctor.
6. Put the cap back on and close the bottle straight after you have used it.
7. Close your eye and press the inner corner of the eye with your finger for about two minutes. This helps to stop the medicine from getting into the rest of the body.
8. The dispenser tip is designed to provide a single drop; therefore, do NOT enlarge the hole of the dispenser tip.
9. After you have used all doses, there will be some medicine left in the bottle. You should not be concerned since the extra amount of medicine has been added and you will get the full amount of medicine that your doctor prescribed. Do not attempt to remove the excess medicine from the bottle.

If you put too many drops in your eye or swallow any of the contents of the container, you should contact your doctor immediately.

It is important to take this medicine as prescribed by your doctor.

If you miss a dose, take it as soon as possible. However, if it is almost time for the next dose, skip the missed dose and go back to your regular dosing schedule.

Do not take a double dose to make up for the forgotten dose.

If you want to stop using this medicine talk to your doctor first.

If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet.

You can also report side effects directly via the national reporting system listed in Yellow Card Scheme Website: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. By reporting side effects you can help provide more information on the safety of this medicine.

• The active substance is dorzolamide. Each ml contains 20 mg dorzolamide (as dorzolamide hydrochloride).
• The other ingredients are Mannitol, Hydroxyethyl Cellulose, Benzalkonium Chloride (as a preservative), Sodium Citrate, Sodium Hydroxide for pH adjustment and Water for injection.

Dorzolamide is a sterile, isotonic, buffered, colourless, slightly viscous solution in a white opaque medium density polyethylene bottle with a sealed dropper tip and a two-piece cap assembly. Each bottle contains 5 mL of the eye drop solution.

Dorzolamide is available in packs containing 1 bottle, 3 bottles or 6 bottles.

Not all pack sizes may be marketed.